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Managed Healthcare Executive •

Solid Bioscience Reports Positive Early Data from Duchenne Gene Therapy Trial

Solid Biosciences reported recent positive data in developing their gene therapy candidate SGT-003. The phase 1/2 INSPIRE DUCHENNE trial results demonstrated that SGT-003 showed an average microdystrophin expression of 110% in the first three participants. In a news release earlier this month, the Charlestown, Massachusetts, company says that treatment with SGT-003 led to significant improvements in muscle health biomarkers.Duchenne muscular dystrophy is a genetic condition that leads to muscle...
Managed Healthcare Executive •

Sarepta Announces Positive Results for Elevidys, Gene Therapy for Duchenne

Sarepta Therapeutics has reported positive results from part two of the EMBARK study, demonstrating the efficacy and safety of the gene therapy Elevidys (delandistrogene moxeparvovec-rokl) in improving functional outcomes for people with Duchenne muscular dystrophy (DMD) who are ambulatoryThe data, shared in Jan.27, 2025, news release, showed that treatment with Elevidys led to significant improvements in muscle function and strength, as well as a reduction in the rate of disease progression.App...
WebMD •

Acyclovir (Zovirax): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not take acyclovir.Your pharmacist can tell you all of the ingredients in the specific acyclovir products they stock.Do not take acyclovir unless it has been prescribed to you by a healthcare provider. Take it as prescribed.Do not share acyclovir with other people, even if they have the same condition as you. It may harm them.Keep acyclovir out of the reach of children.Be sure to drink plenty of fluids while you are...
WebMD •

Vivjoa (oteseconazole): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not take Vivjoa.Your pharmacist can tell you all of the ingredients in Vivjoa.Able to Become Pregnant. People who are able to get pregnant or have not gone through menopause should not take Vivjoa.Pregnancy. Do not take Vivjoa if you are pregnant or plan to become pregnant. If you become pregnant, contact your healthcare provider right away. See the Pregnancy section for more details.Breastfeeding. Do not take Vivjo...
WebMD •

Voriconazole (Vfend): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

The most common side effects of voriconazole are listed below. Side effects can vary based on age. Tell your healthcare provider if you have any of these side effects that bother you.There may be other side effects of voriconazole that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health...
Managed Healthcare Executive •

Can Pain Be Patched Up?

Clinicians, patients and some experts have viewed transdermal anti-inflammatory patches as a promising way to bypass the side effects and other problems associated with oral and injectable delivery of anti-inflammatory medications.A systematic review and meta-analysis published in November in the journal Pain Management may give some pause. It found that transdermal anti-inflammatory patches did not have sufficient evidence to support clinically significant impact on managing short-term and long...
WebMD •

Cresemba (isavuconazonium): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not take Cresemba.Your pharmacist can tell you all of the ingredients in Cresemba.Drug Interactions. Cresemba should not be used while you are using certain other medicines. Before using Cresemba, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.Familial Shor...
Managed Healthcare Executive •

Don’t Want to Hear It: Sound Elicited Pain

Imagine a world where the simple sounds of daily life trigger physical pain. For individuals with pain hyperacusis, also known as noxacusis, this is a distressing reality. A recent study from November in The Journal of Pain sheds light on the clinical characteristics, underlying mechanisms, and pain management strategies for this underrecognized condition. The research highlighted the urgent need for multidisciplinary care and further investigation into this challenging auditory disorder by expl...
WebMD •

Acyclovir topical (Zovirax): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not use topical acyclovir.Your pharmacist can tell you all of the ingredients in the specific topical acyclovir products they stock.Do not use topical acyclovir unless it has been prescribed to you by a healthcare provider. Use it as prescribed. Ask your healthcare provider if you are not sure where or how to apply topical acyclovir.Do not share topical acyclovir with other people, even if they have the same conditi...
WebMD •

Docosanol (Abreva): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not use docosanol.Your pharmacist can tell you all of the ingredients in the specific docosanol product you are using.Follow the instructions that come with the product to be sure you use docosanol properly. Ask your healthcare provider if you are not sure how or where to apply docosanol. Do not share docosanol with other people, even if they have the same condition as you. This may spread the infection. Keep docosa...
WebMD •

Penciclovir (Denavir): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not use penciclovir.Your pharmacist can tell you all of the ingredients in the specific penciclovir products they stock.Do not use penciclovir unless it has been prescribed to you by a healthcare provider. Use it as prescribed.Do not share penciclovir with other people, even if they have the same condition as you. It may harm them.Keep penciclovir out of the reach of children.You should start penciclovir as soon as...
WebMD •

Xerese (acyclovir/hydrocortisone): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not use Xerese.Your pharmacist can tell you all of the ingredients in Xerese.Do not use Xerese unless it has been prescribed to you by a healthcare provider. Use it as prescribed.Do not share Xerese with other people, even if they have the same condition as you. It may harm them.Keep Xerese out of the reach of children.Start using this medicine as soon as possible after you first notice cold sore symptoms, such as t...
WebMD •

Sitavig (acyclovir): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not use Sitavig.Your pharmacist can tell you all of the ingredients in Sitavig.Do not use Sitavig unless it has been prescribed to you by a healthcare provider. Use it as prescribed.Do not share Sitavig with other people, even if they have the same condition as you. It may harm them.Keep Sitavig out of the reach of children.Do not remove Sitavig from the blister pack until you are ready to use it. Your hands should...
WebMD •

Famciclovir (Famvir): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Allergies to Ingredients. People who are allergic to any of the following should not take famciclovir.Your pharmacist can tell you all of the ingredients in the specific famciclovir products they stock.Do not take famciclovir unless it has been prescribed to you by a healthcare provider. Take it as prescribed.Do not share famciclovir with other people, even if they have the same condition as you. It may harm them.Keep famciclovir out of the reach of children.Take famciclovir as soon as possible...
Managed Healthcare Executive •

Knee Pain: Another Ailment That Semaglutide Might Help With

A study published in The New England Journal of Medicine has demonstrated the potential of semaglutide for alleviating knee osteoarthritis pain in obese individuals in addition to weight loss. Participants treated with semaglutide, sold under the name Ozempic for diabetes and Wegovy for weight loss, experienced a significantly greater reduction in body weight compared to those receiving a placebo while also achieving substantially decreased knee osteoarthritis pain and improved physical function...
Medical News Today •

Imodium cost: Savings options and more

Imodium cost As with all medications, the cost of Imodium can vary. Factors that may affect the price you’ll pay include:your treatment planthe pharmacy where you buy Imodiumthe form of Imodium you takeImodium is available over the counter (OTC) without a prescription from a healthcare professional. To find out what the cost of Imodium will be for you, talk with your doctor, pharmacist, or insurance provider.

Imodium cost

Imodium cost

As with all medications, the cost of Imodium can vary. Fac...
Managed Healthcare Executive •

Researchers to Clinicians: Don’t Neglect the Neuropsychiatric Symptoms of Friedreich’s Ataxia

A study recently published in Nature Scientific Reports explored neuropsychiatric symptoms in individuals with Friedreich’s ataxia (FRDA), a hereditary neurodegenerative disorder. FRDA patients demonstrated higher rates of depression and anxiety and decreased motivation compared with healthy controls.Moreover, neuropsychiatric symptoms in FRDA may be a consequence of neurodegeneration and the burden of living with a progressive disease.The cerebellum is the part of the brain that is responsible...
Managed Healthcare Executive •

Gabapentinoid Use Linked to Risk of Hip Fracture

A study published in JAMA Network earlier this month investigated the relationship between the use of gabapentinoids, a class of drugs that includes pregabalin (Lyrica) and gabapentin (Neurontin), and the risk of hip fractures. Similar to previous studies linking antidepressant and benzodiazepine use to hip fractures, the research showed that gabapentinoid use was also associated with in elevated risk of hip fractures among older adults, especially in those identified as frail or with chronic ki...
Optum Perks •

Gabapentin alternatives: Prescription and OTC options

Doctors often prescribe gabapentin for conditions like fibromyalgia, anxiety, and nerve pain caused by shingles or diabetes. They may also prescribe it to reduce seizures.In the United States, gabapentin is only available by prescription. The Food and Drug Administration (FDA) has not approved any over-the-counter (OTC) formulations.Need a diagnosis or prescription quickly? Optum Perks offers personalized on-demand care in as little as 15 minutes with no video or appointment required. For $25, a...
Optum Perks •

How do I get the best results from tretinoin?

Tretinoin is a topical retinoid that people often use to treat acne, reduce wrinkles, and improve skin texture. It comes in cream, gel, and solution forms. Doctors usually prescribe it under different brand names, such as:In the United States, tretinoin typically requires a prescription. But some lower-strength retinoids, like adapalene (Differin), are available over the counter.Need a diagnosis or prescription quickly? Optum Perks offers personalized on-demand care in as little as 15 minutes wi...
Healthline •

Naltrexone and Interactions: Other Drugs, Supplements, and More

Does Naltrexone interact with other drugs?Before you start taking naltrexone, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions. (To learn whether naltrexone interacts with herbs, vitamins, or supplements, see the “Are there other interactions with naltrexone?” section.)If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.The...
Medical News Today •

Glyxambi and interactions: Other drugs, alcohol, and more

Glyxambi interactions with other medications   Before you start treatment with Glyxambi, tell your doctor and pharmacist which prescription, over-the-counter (OTC), and other medications you take. By sharing this information with them, you may help prevent possible interactions. (To learn whether Glyxambi interacts with supplements, herbs, or vitamins, see the “Glyxambi and other interactions” section.)If you have questions about drug interactions that may affect you, ask your doctor or pharmaci...
Medical News Today •

Exondys 51 side effects: What they are and how to manage them

More common side effects of Exondys 51 Exondys 51 can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.These are just a few of the more common side effects reported by people who received Exondys 51 in clinical trials:vomitingproblems with balance*contact dermatitis** For more infor...
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